● Lefuba la Mycobacterium
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Mycobacterium Tuberculosis Nucleic Acid le Rifampicin(RIF)，Resistance(INH)
Setsi sena se sebelisetsoa ho lemoha boleng ba in vitro ea Mycobacterium tuberculosis DNA ka sekhohlela sa motho, setso se tiileng (LJ Medium) le setso sa metsi (MGIT Medium), bronchial lavage fluid, le liphetoho tse sebakeng sa 507-533 amino acid codon (81bp, rifampicin resistance genering general resistance), hammoho le liphetoho tse libakeng tse ka sehloohong tsa phetoho ea Mycobacterium tuberculosis isoniazid resistance.E fana ka thuso ho hlahlobisiseng tšoaetso ea lefuba la Mycobacterium, 'me e lemoha liphatsa tsa lefutso tse ka sehloohong tsa rifampicin le isoniazid, tse thusang ho utloisisa khanyetso ea meriana ea lefuba la Mycobacterium le tšoaelitsoeng ke mokuli.
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Mycobacterium Tuberculosis INH Phetoho
Setsi sena se loketse ho lemoha boleng ba libaka tse ka sehloohong tsa phetoho ea li-sputum tsa batho tse bokelitsoeng ho bakuli ba Tubercle bacillus positive tse lebisang ho mycobacterium lefuba INH: InhA promoter region -15C>T, -8T>A, -8T>C; Sebaka sa papatso sa AhpC -12C>T, -6G>A; phetoho ea homozygous ea KatG 315 codon 315G>A, 315G>C.
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Mycobacterium Tuberculosis Rifampicin Resistance
Setsi sena se loketse ho lemoha boemo ba phetoho ea homozygous sebakeng sa 507-533 amino acid codon ea gene ea rpoB e bakang Mycobacterium tuberculosis rifampicin resistance.
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Mycobacterium Tuberculosis Nucleic Acid le Rifampicin Resistance
Setsi sena se loketse tlhahlobo ea boleng ba Mycobacterium tuberculosis DNA disampole tsa sekhohlela sa motho in vitro, hammoho le phetoho ea homozygous sebakeng sa 507-533 amino acid codon ea mofuta oa rpoB e bakang Mycobacterium tuberculosis rifampicin resistance.
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DNA ea Mycobacterium Lefuba
E loketse ho lemoha boleng ba Mycobacterium lefuba DNA ka lisampole tsa sekhohlela sa kliniki ea motho, 'me e loketse tlhahlobo e thusang ea tšoaetso ea lefuba la Mycobacterium.
