● Lefuba la Mycobacterium
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Mycobacterium Tuberculosis Nucleic Acid le Rifampicin(RIF)，Isoniazid Resistance(INH)
Sehlahisoa sena se loketse tlhahlobo ea boleng ba Mycobacterium tuberculosis DNA ho lisampole tsa sekhohlela sa motho in vitro, hammoho le phetoho ea homozygous sebakeng sa 507-533 amino acid codon (81bp, sebaka se khethollang rifampicin) ea mofuta oa rpoB o bakang lefuba la Mycobacterium. ho hanyetsa rifampicin.
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Mycobacterium Tuberculosis Isoniazid Resistance Phetoho
Setsi sena se loketse ho lemoha boleng ba libaka tse ka sehloohong tsa phetoho ea li-sputum tsa batho tse bokelitsoeng ho bakuli ba Tubercle bacillus positive tse lebisang ho mycobacterium lefuba la isoniazid resistance: InhA promoter region -15C>T, -8T>A, -8T>C;Sebaka sa papatso sa AhpC -12C>T, -6G>A;phetoho ea homozygous ea KatG 315 codon 315G>A, 315G>C.
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Mycobacterium Tuberculosis Rifampicin Resistance
Setsi sena se loketse ho lemoha boemo ba phetoho ea homozygous sebakeng sa 507-533 amino acid codon ea gene ea rpoB e bakang Mycobacterium tuberculosis rifampicin resistance.
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Mycobacterium Tuberculosis Nucleic Acid le Rifampicin Resistance
Setsi sena se loketse tlhahlobo ea boleng ba Mycobacterium tuberculosis DNA disampole tsa sekhohlela sa motho in vitro, hammoho le phetoho ea homozygous sebakeng sa 507-533 amino acid codon ea mofuta oa rpoB e bakang Mycobacterium tuberculosis rifampicin resistance.
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Mycobacterium Tuberculosis INH Resistance
Setsi sena se sebelisetsoa ho lemoha ka mokhoa oa boleng phetoho ea liphatsa tsa lefutso tsa 315th amino acid ea katG gene (K315G> C) le phetoho ea liphatsa tsa lefutso tsa sebaka sa mohlohlelletsi oa lefutso la InhA (- 15 C> T).
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DNA ea Mycobacterium Lefuba
E loketse ho lemoha boleng ba Mycobacterium lefuba DNA ka lisampole tsa sekhohlela sa kliniki ea motho, 'me e loketse tlhahlobo e thusang ea tšoaetso ea lefuba la Mycobacterium.
