Motho TEL-AML1 Fusion Gene Phetoho
Lebitso la sehlahisoa
HWTS-TM016 Human TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiology
Acute lymphoblastic leukemia (ALL) ke lefu le atileng haholo bongoaneng.Lilemong tsa morao tjena, acute leukemia (AL) e fetohile ho tloha ho mofuta oa MIC (morphology, immunology, cytogenetics) ho ea ho mofuta oa MICM (tlatsetso ea tlhahlobo ea baeloji ea limolek'hule).Ka 1994, ho ile ha sibolloa hore fusion ea TEL bongoaneng e bakoa ke translocation e sa tloaelehang ea chromosomal t(12;21)(p13;q22) ho B-lineage acute lymphoblastic leukemia (ALL).Ho tloha ha ho sibolloa mofuta oa motsoako oa AML1, mofuta oa fusion oa TEL-AML1 ke tsela e molemohali ea ho ahlola boemo ba bana ba nang le acute lymphoblastic leukemia.
Channel
| FAM | TEL-AML1 mofuta oa motsoako |
| ROX | Taolo ea ka hare |
Tekheniki Parameters
| Polokelo | ≤-18℃ |
| Shelf-bophelo | Likhoeli tse 9 |
| Mofuta oa Mohlala | mohlala oa moko oa masapo |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000Likopi/mL |
| Tse khethehileng | Ha ho na cross-reactivity lipakeng tsa kits le mefuta e meng ea fusion e kang BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa fusion genes. |
| Lisebelisoa tse sebetsang | Applied Biosystems 7500 Real-Time PCR Systems Applied Biosystems 7500 Fast Real-Time PCR Systems QuantStudio®5 Nako ea 'Nete ea PCR Systems Litsamaiso tsa PCR tsa nako ea sebele tsa SLAN-96P Sesebelisoa sa PCR sa LightCycler®480 Real-Time LineGene 9600 Plus Nako ea 'Nete ea PCR ea ho Fumana Sistimi MA-6000 Real-Nako Quantitative Thermal Cycler Sistimi ea PCR ea Nako ea 'Nete ea BioRad CFX96 BioRad CFX Opus 96 Real-Nako PCR System |
Phallo ea Mosebetsi
RNAprep Pure Blood Total RNA Extraction Kit (DP433).
