Cyp2c9 le vkorc1 Gesion PeolyMemorfism
Lebitso la Product
HWTS-GEE014A-PRPP2C9 le VKPORC1 le VKORC1 TICE TICE PEYMORphism ea TICKIM TICE (Fluorescence PCR)
Setifikeiti
CE / TFDA
Epidphiology
WarFarrin ke monko oa ntoa oa molomo o sebelisoang hangata ho tliliniki hona joale, haholo-holo ho thibelo le kalafo ea litsie tsa Thromboembialic. Leha ho le joalo, Warfin o na le fensetere ea kalafo mme o fapana haholo le merabe le batho ka bomong. Lipalo-palo li bontšitse hore phapang ea tekanyetso e tsitsitseng ho batho ba fapaneng e ka ba makhetlo a fetang 20. Ho tsoa mali habohloko ho hlaha ka 152% ea bakuli ba tšoeroeng ntoa selemo se seng le se seng, seo e leng 3.5% e fetoha mali a bolaeang. Lithuto tsa pharmacoonic li bontšitse hore enztphisphism ea liphatsa tsa lefutso e kenang ea lefutso enczyme vkilebolin e ama cyp2c9 ea tirfarin ke karolo ea bohlokoa ea ntoa ea ntoa. Ntoa ke Inhitha e ikhethang ea li-vithamine K Epoxide e eketsehileng (VKORC1), 'me ka hona e fana ka li-synthesis tse amanang le vithamine K. Boithuto bo bongata bo bontšitse hore papali ea "polymorfism ea VKORC1 ea VKORC1 e ama ntho ea bohlokoa ka ho fetisisa e amang peiso le liphapang tsa motho ka mong ho tekanyetso e hlokahalang ea ntoa. WarFARIN e metatloatsoa ke cyp2c9, le basebeletsi ba eona ba liehang ho fokola haholo mocheso oa ntoa oa ntoa. Batho ba sebelisang ntoa ea ntoa ba na le kotsi e phahameng (habeli ho isa makhetlo a mabeli ho isa makhetlo a mararo) ea mali mohatong oa ho sebelisoa.
Channel
| FMAM | Vkorc1 (-1639g> a) |
| Cy5 | Cyp2c9 * 3 |
| Video / Hex | IC |
Litekanyetso tsa tekheniki
| Polokelo | Metsi: ≤-18 ℃ |
| Shell-Bophelo | Likhoeli tse 12 |
| Mofuta oa SIMON | Malinyane a Edta e Nchafalitsoeng |
| CV | ≤ 40.0% |
| Lod | 1.0NG / μl |
| TLHOKOMELISO | Ha ho na ho fana ka maikutlo ka ho lekanya le leng le le leng la tlhaho ea motho (cyp2c19 Gener, motho Rpn2 Genel) Liphetoho tsa cyp2c9 * 13 le VKORC1 (3730G> A) ka ntle ho khetho ea ho lemoha ho khethoa ha sehlopha sena |
| Lisebelisoa tse sebetsang | E sebelisoa BIOSSYSTEMS 7500 Real-Nako ea Pruc Biosstems ea BiosStems 7500 ea Nako e sa Ts'oerehileng ea Nako ea Nako ea Nako Quantshetstudio®5 Real-Nako ea Likarolo Slan-96p Real-Nako ea Likarolo tsa nako ea ly-Nako Lightcycler®480 Real-Nako ea PCR ea Pru Linegene 9600 le sistimi ea nako ea nako ea nako ea nako Ma-6000 ea 'nete ea The Larmal Cyclement Cyclement Biorad CFX96 Real-Nako ea Prust Biorad Cfx OPS 96 Real-Nako ea Prust |
Phallo ea mosebetsi
Khoebo e khothalelitsoeng: Macro & Micro-Ter Viline DNA / HWTS-3001 3006).
