Human Eml4-Alk FONLONY

Kit ena e sebelisetsoa ho lemoha mefuta ea litheolelo tsa EML4-Alk FONLO SMONPLE E BANG KAMOO BA FANG CEN-KOLONE CERSION CONY CELLY CELLY CEN-KOLOBETSO EA METSI KOLOTSO EA MPHONE CELLE CITY CELLY CELLY CELLY CEN-KOLOBETSO EA METSI SE SEBELETSA CELLY LY-KOLOBETSO EA METSI E MOLEMO OA CONY FELLY CELLY CEN-KOLOFER. Liphetho tsa liteko ke tsa ho buuoa ka cliniki feela mme ha lia lokela ho sebelisoa e le eona feela motheo oa kalafo e ikhethileng ea bakuli. Baetsi ba lingaka ba lokela ho ahlola likhatho tse ngata liphethong tse kang boemo ba mokuli, pontšo ea lithethefatsi, karabelo ea kalafo le lisosa tse ling tsa kalafo. Kankere ea Lung ke hlako e atisa ho utloisa bohloko ka ho fetisisa lefatšeng ka bophara, le 80% ~ 85% ea linyeoe ke selefounu (NSCLC). Gene Fusion of Echinoderm Microtube e amanang le Echinoderm Microtubule-Like 1 Lipalo tsa milione. Bonyane li-fusion tse 20 li fumanoe, tse ling tseo li-fusion tse 12 li leng teng ka tafoleng 1 (e13; a20), accounting ea ka 33% le 29% ea bakuli ba nang le EML4-Alk Fusion TICK CK NSCC, ka ho latellana. ALK inhibitors e emeloang ke Crizotinibibin ke Lithethefatsi tse Khoetsang Lithethefatsi tse Phethahetseng Liphetoho tsa Alk Gesion. Ka ho thibela tšebetso ea alk tyronine lebaleng la eona la ho tsoala litseleng, ho fihlela pheko ea lisele tsa tumir, ho etsa kalafo ea lisele tsa tumir bakeng sa litlhare tse pakiloeng. Boithuto ba bongaka bo bontšitse hore Cricotinib e na le sekhahla se sebetsang ho feta 61% ho bakuli ba nang le liphetoho tsa Eml4-Alk FONUNDES, ha e se e se na phello ea bakuli ba mofuta o hlaha. Ka hona, ho khetholloa ha maemo a Eml4-alk