Khopolo ea hlahala
Hlahala ke ntho e ncha e phelang e entsoeng ke ho ata ho sa tloaelehang ha lisele tsa 'mele, tse atisang ho iponahatsa e le boima bo sa tloaelehang ba lisele tsa 'mele (leqhubu) karolong ea sebaka sa' mele. Ho thehoa ha hlahala ke phello ea bothata bo tebileng ba taolo ea kholo ea lisele tlas'a ketso ea lintlha tse sa tšoaneng tsa tumorigenic. Ho ata ho sa tloaelehang ha lisele tse lebisang ho thehoeng ha hlahala ho bitsoa neoplastic proliferation.
Ka 2019, Cancer Cell e phatlalalitse sengoloa haufinyane. Bafuputsi ba fumane hore metformin e ka thibela kholo ea hlahala haholo maemong a ho itima lijo, mme ba fana ka tlhahiso ea hore tsela ea PP2A-GSK3β-MCL-1 e kanna ea ba sepheo se secha sa kalafo ea tumor.
Phapang e kholo pakeng tsa hlahala e kotsi le hlahala e kotsi
Sehlahala se nang le bokooa: khōlo e liehang, capsule, kholo ea ho ruruha, ho thellela ho ea ho ama, moeli o hlakileng, ha ho na metastasis, ka kakaretso prognosis e ntle, matšoao a khatello ea sebaka seo, hangata ha ho 'mele oohle, hangata ha o bake lefu la bakuli.
Sehlahala se kotsi (kankere): ho hōla ka potlako, khōlo e hlaselang, ho khomarela lisele tse potolohileng, ho se khone ho sisinyeha ha ho ama, moeli o sa hlakang, metastasis e bonolo, ho iphetetsa habonolo ka mor'a phekolo, feberu e fokolang, takatso e mpe ea lijo qalong, ho lahleheloa ke boima ba 'mele, ho fokotseha ho matla, phokolo ea mali le feberu qetellong ea nako, joalo-joalo Haeba e sa phekoloe ka nako, hangata e lebisa lefung.
"Hobane lihlahala tse kotsi le lihlahala tse kotsi ha li na feela lipontšo tse sa tšoaneng tsa kliniki, empa ho bohlokoa le ho feta, tsoelo-pele ea bona e fapane, kahoo hang ha u fumana lesela 'meleng oa hao le matšoao a ka holimo, u lokela ho batla keletso ea bongaka ka nako."
Phekolo ea motho ka mong ea hlahala
Human Genome Project le International Cancer Genome Project
Human Genome Project, e ileng ea thakholoa ka molao United States ka 1990, e ikemiselitse ho notlolla likhoutu tsohle tsa liphatsa tsa lefutso tse ka bang 100,000 'meleng oa motho le ho hula mefuta e mengata ea liphatsa tsa lefutso tsa motho.
Ka 2006, Morero oa Machaba oa Genome oa Kankere, o kopantsoeng ke linaha tse ngata, ke lipatlisiso tse ling tse kholo tsa saense ka mor'a morero oa Human Genome.
Mathata a mantlha a kalafo ea tumor
Tlhahlobo le kalafo ea motho ka mong = Tlhahlobo ea motho ka mong + lithethefatsi tse lebisitsoeng
Bakeng sa bakuli ba bangata ba fapaneng ba tšoeroeng ke lefu le le leng, mokhoa oa phekolo ke ho sebelisa meriana e tšoanang le litekanyetso tse tloaelehileng, empa ha e le hantle, bakuli ba fapaneng ba na le phapang e khōlō liphellong tsa phekolo le liketso tse mpe, 'me ka linako tse ling phapang ena e bile e bolaeang.
Phekolo ea lithethefatsi e reretsoeng e na le litšobotsi tsa ho bolaea lisele tsa hlahala ka mokhoa o ikhethileng ntle le ho bolaea kapa ho senya lisele tse tloaelehileng ka seoelo, tse nang le litlamorao tse nyane, tse ntlafatsang bophelo le phello ea kalafo ea bakuli ka nepo.
Hobane kalafo e lebisitsoeng e etselitsoe ho hlasela limolek'hule tse tobileng, hoa hlokahala ho bona liphatsa tsa lefutso tsa tumor le ho bona hore na bakuli ba na le sepheo se tšoanang pele ba noa lithethefatsi, e le hore ba ka khona ho phekola.
Ho lemoha liphatsa tsa lefutso tsa hlahala
Ho lemoha liphatsa tsa lefutso tsa hlahala ke mokhoa oa ho sekaseka le ho hlophisa DNA/RNA ea lisele tsa hlahala.
Bohlokoa ba ho lemoha liphatsa tsa lefutso tsa tumor ke ho tataisa khetho ea lithethefatsi ea phekolo ea lithethefatsi (lithethefatsi tse lebisitsoeng, li-immune checkpoint inhibitors le AIDS e meng e ncha, phekolo ea morao-rao), le ho bolela esale pele hore na ho tla etsahala'ng le ho khutla hape.
Litharollo tse fanoeng ke Acer Macro & Micro-Test
Motho EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR）
E sebelisoa bakeng sa tlhahlobo ea boleng ba liphetoho tse tloaelehileng ho exon 18-21 ea EGFR gene ho bakuli ba mofets'e bao e seng ba banyenyane ba mofets'e oa mofetše oa matšoafo ka har'a vitro.
1. Kenyelletso ea taolo ea boleng ba litšupiso tsa kahare ho sistimi e ka lekola ts'ebetso ea liteko ka botlalo le ho netefatsa boleng ba liteko.
2. Kutloelo-bohloko e phahameng: tekanyo ea phetoho ea 1% e ka fumanoa ka mokhoa o tsitsitseng ka morao ho 3ng / μL mofuta oa hlaha oa motsoako oa nucleic acid reaction.
3. Boiphihlelo bo phahameng: ha ho na karabelo e fapaneng le liphetho tsa ho sibolloa ha DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
KRAS 8 Mutations Detection Kit (Fluorescence PCR)
Mefuta e robeli ea liphetoho ho li-codon 12 le 13 tsa lefutso la K-ras tse sebelisetsoang ho lemoha boleng ba DNA e ntšitsoeng likarolong tsa pathological tse kentsoeng ke parafine in vitro.
1. Kenyelletso ea taolo ea boleng ba litšupiso tsa kahare ho sistimi e ka lekola ts'ebetso ea liteko ka botlalo le ho netefatsa boleng ba liteko.
2. Kutloelo-bohloko e phahameng: tekanyo ea phetoho ea 1% e ka fumanoa ka mokhoa o tsitsitseng ka morao ho 3ng / μL mofuta oa hlaha oa motsoako oa nucleic acid reaction.
3. Boiphihlelo bo phahameng: ha ho na karabelo e fapaneng le liphetho tsa ho sibolloa ha DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
Batho ba ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
E sebelisoa ho bona ka mokhoa o nepahetseng mefuta e 14 ea phetoho ea mofuta oa fusion ea ROS1 ho bakuli ba mofetše oa mofetše oa matšoafo oa sele e seng e nyane ka har'a vitro.
1. Kenyelletso ea taolo ea boleng ba litšupiso tsa kahare ho sistimi e ka lekola ts'ebetso ea liteko ka botlalo le ho netefatsa boleng ba liteko.
2. Kutloelo-bohloko e phahameng: Likopi tsa 20 tsa phetoho ea fusion.
3. Boiphihlelo bo phahameng: ha ho na karabelo e fapaneng le liphetho tsa ho sibolloa ha DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
Motho EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
E sebelisetsoa ho lemoha ka mokhoa o nepahetseng mefuta e 12 ea phetoho ea EML4-ALK fusion ea lefutso ho bakuli ba kankere ea matšoafo e seng e nyenyane ea lisele ka hare ho vitro.
1. Kenyelletso ea taolo ea boleng ba litšupiso tsa kahare ho sistimi e ka lekola ts'ebetso ea liteko ka botlalo le ho netefatsa boleng ba liteko.
2. Kutloelo-bohloko e phahameng: Likopi tsa 20 tsa phetoho ea fusion.
3. Boiphihlelo bo phahameng: ha ho na karabelo e fapaneng le liphetho tsa ho sibolloa ha DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
Human BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR)
E sebelisoa ho bona ka mokhoa oa boleng phetoho ea mofuta oa BRAF V600E lisampoleng tsa lisele tse kentsoeng ka parafine tsa melanoma ea motho, mofetše oa mala, mofetše oa qoqotho le mofetše oa matšoafo ka har'a vitro.
1. Kenyelletso ea taolo ea boleng ba litšupiso tsa kahare ho sistimi e ka lekola ts'ebetso ea liteko ka botlalo le ho netefatsa boleng ba liteko.
2. Kutloelo-bohloko e phahameng: tekanyo ea phetoho ea 1% e ka fumanoa ka mokhoa o tsitsitseng ka morao ho 3ng / μL mofuta oa hlaha oa motsoako oa nucleic acid reaction.
3. Boiphihlelo bo phahameng: ha ho na karabelo e fapaneng le liphetho tsa ho sibolloa ha DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
| Ntho No | Lebitso la Sehlahiswa | Tlhaloso |
| HWTS-TM006 | Motho EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 liteko / kit 50 liteko / kit |
| HWTS-TM007 | Human BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR) | 24 liteko / kit 48 liteko/kit |
| HWTS-TM009 | Batho ba ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 liteko / kit 50 liteko / kit |
| HWTS-TM012 | Motho EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR） | 16 liteko/kit 32 liteko/kit |
| HWTS-TM014 | KRAS 8 Mutations Detection Kit (Fluorescence PCR) | 24 liteko / kit 48 liteko/kit |
| HWTS-TM016 | Batho ba TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 liteko / kit |
| HWTS-GE010 | Human BCR-ABL Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 liteko / kit |
Nako ea poso: Apr-17-2024