Sampole e Iketsetsang Karabo ka Botlalo C. Ho Fumana Tshwaetso e Fapaneng

Ke eng e bakang tšoaetso ea C. Diff?

Tšoaetso ea C.Diff e bakoa ke baktheria e tsejoang e leClostridioides difficile (C. difficile), eo hangata e dulang ka maleng ntle le kotsi. Leha ho le jwalo, ha ho na le bothata ba ho leka-lekana ha dibaktheria mala, hangata ho sebediswa dithibela-mafu tse pharaletseng, C. difficile e ka hola haholo mme ya hlahisa chefo, e leng se lebisang tshwaetsong.

Baktheria ena e teng ka bobelichefo e bakang chefole mefuta e seng ya chefo, empa ke mefuta ya chefo feela (chefo A le B) e bakang lefu. Di baka ho ruruha ka ho sitisa disele tsa epithelial tsa mala. Chefo A ke chefo e senyang lera la mala, e eketsang ho kenella ha mmele, mme e hohela disele tsa mmele tse lokollang di-cytokine tse ruruhisang. Chefo B, cytotoxin e matla haholo, e shebana le cytoskeleton ya actin ya disele, e leng se lebisang ho pota-poteng ha disele, ho arohana ha tsona, mme qetellong lefu la disele. Hammoho, chefo ena e baka tshenyo ya dinama le karabelo e matla ya mmele ya ho itšireletsa mafung, e iponahatsang e le colitis, letshollo, mme maemong a boima, pseudomembranous colitis—ho ruruha ho tebileng ha mala a maholo.

JoangC. Phapangho jaleha?

C.Diff e ata habonolo. E fumaneha lipetleleng, hangata e fumanoa li-ICU, matsohong a basebetsi ba sepetlele, fatše le li-handrails tsa sepetlele, li-thermometer tsa elektroniki, le lisebelisoa tse ling tsa bongaka...

Mabaka a Kotsi bakeng sa Tšoaetso ea C. Diff

• ●Ho kena sepetlele nako e telele;

• ●Kalafo ea likokoana-hloko;

• ●Lithethefatsi tsa chemotherapy;

• ●Opereishene ea morao tjena (matsoho a mpa, ho patoa ha mpa, opereishene ea mala a maholo);

• ●Phepo e nepahetseng ea mpa le mala;

• ●Tšoaetso ea pele ea C. diff;

Matšoao a tšoaetso ea C. Diff

Tšoaetso ea C. diff e ka ba e sa phutholohang haholo. Batho ba bangata ba na le letšollo le sa phutholohang ka mpeng. Matšoao a tloaelehileng haholo ke: letšollo, bohloko ba mpa, ho nyekeloa ke pelo, ho lahleheloa ke takatso ea lijo, feberu.

Ha tšoaetso ea C. diff e ntse e mpefala le ho feta, ho tla ba le nts'etsopele ea mofuta o rarahaneng haholoanyane oa C. diff o tsejoang e le colitis, pseudomembranous enteritis esita le lefu.

Tlhahloboea tšoaetso ea C. Diff

Setso sa Baktheria:E bonolo empa e nka nako e telele (matsatsi a 2-5), ha e kgone ho kgetholla mefuta ya chefo le e seng chefo;

Setso sa Chefo:e hlwaya mefuta e chefo e bakang mafu empa e nka nako e telele (matsatsi a 3-5) mme e sa amehe haholo;

Ho lemoha GDH:e potlakile (lihora tse 1-2) ebile e theko e tlase, e na le kutlo e matla haholo empa e ke ke ea khetholla mefuta ea chefo le e seng chefo;

Teko ea ho se be le chefo ea sele (CCNA):e lemoha chefo A le B ka kutlo e phahameng empa e nka nako (matsatsi a 2-3), mme e hloka dibaka tse ikgethang le basebetsi ba koetlisitsweng;

Chefo A/B ELISA: Teko e bonolo le e potlakileng (lihora tse 1-2) ka kutlo e tlase le liphoso tse fosahetseng tse etsahalang khafetsa;

Liteko tsa ho Eketsa Asiti ea Nucleic (NAATs): E potlakile (lihora tse 1-3) 'me e na le kutloelo-bohloko haholo le e tobileng, e lemoha liphatsa tsa lefutso tse ikarabellang bakeng sa tlhahiso ea chefo;

Ho phaella moo, liteko tsa ho hlahloba mala, tse kang CT scans le X-rays, le tsona li ka sebelisoa ho thusa ho fumana C. diff le mathata a C. diff, a kang colitis.

Kalafo ea tšoaetso ea C. Diff

Mekhoa e mengata ea phekolo e fumaneha bakeng saC. tšoaetso e fapanengKa tlase ke dikgetho tse ntle ka ho fetisisa:

• ●Lithibela-mafu tse nooang tse kang vancomycin, metronidazole kapa fidaxomicin li sebelisoa hangata kaha meriana e ka feta tsamaisong ea tšilo ea lijo 'me ea fihla ka mpeng moo libaktheria tsa C. diff li lulang teng.

• ●Metronidazole e kenngoang ka har'a vein e ka sebelisoa bakeng sa kalafo haeba tšoaetso ea C. diff e le mpe haholo.

• ●Ho fetisetsa di-microbiota tsa mantle ho bontshitse katleho ho phekoleng ditshwaetso tse atileng tsa C. diff le ditshwaetso tse matla tsa C. diff tse sa arabeleng dithibela-mafu.

• ●Ho ka hlokahala opereishene bakeng sa maemo a boima.

Tharollo ea tlhahlobo ho tsoa ho MMT

Ho arabela tlhoko ea ho lemoha C. difficile ka potlako le ka nepo, re hlahisa Kit ea rona e ncha ea ho lemoha Nucleic Acid bakeng sa chefo ea Clostridium difficile gene ea A/B, re matlafatsa litsebi tsa tlhokomelo ea bophelo ho etsa tlhahlobo ea pele le e nepahetseng le ho tšehetsa ntoa khahlanong le tšoaetso e fumanoeng sepetlele.

图片链接:

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  ●Ho ba le kutlo e phahameng: E lemoha ho fihlela ho200 CFU/mL,;

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  ●Sepheo se Nepahetseng: E khetholla ka nepo chefo ea C. difficile A/B gene, e fokotsa lintho tse fosahetseng tse ntle;

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  ●Ho Fumana Pathogen ka ho Otloloha: E sebelisa liteko tsa nucleic acid ho khetholla liphatsa tsa chefo ka ho toba, e theha tekanyetso ea khauta bakeng sa tlhahlobo.

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  ●E lumellana ka botlalo lelisebelisoa tse tloaelehileng tsa PCR tse sebetsanang le lilaboratori tse ngata;

Mohlala oa KaraboTharollo ho Macro & Micro-Test's AIO800 Mobile PCR Lab

 

• ●Boiketsetso ba Sampole-ho-Araba – Kenya lipeipi tsa sampole tsa mantlha (1.5–12 mL) ka kotloloho, ho felisa ho kenya lipeipi ka letsoho. Ho ntša, ho eketsa le ho lemoha li etsoa ka boiketsetso ka botlalo, ho fokotsa nako ea ho sebetsa le liphoso tsa batho.

• ●Tšireletso ea Tšilafalo ea Mekhahlelo e Robeli - Phallo ea moea e tataisoang, khatello e mpe, ho sefa HEPA, ho bolaea likokoana-hloko tsa UV, likarabelo tse koetsoeng, le tšireletso e 'ngoe e kopaneng li sireletsa basebetsi le ho netefatsa liphetho tse tšepahalang nakong ea liteko tse nang le phallo e phahameng.

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