Carbapenemase

Tlhaloso e Khutšoanyane:

Setsi sena se sebelisetsoa ho lemoha boleng ba NDM, KPC, OXA-48, IMP le VIM carbapenemases e hlahisoang ka lisampole tsa baktheria tse fumanoang ka mor'a setso sa vitro.

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lebitso la sehlahisoa

HWTS-OT085E/F/G/H -Carbapenemase Detection Kit (Colloidal Gold)

Epidemiology

Lithibela-mafu tsa Carbapenem ke lithibela-mafu tse sa tloaelehang tsa β-lactam tse nang le li-antibacterial tse pharaletseng ka ho fetesisa le ts'ebetso e matla ea antibacterial.^[1].Ka lebaka la botsitso ba eona ho β-lactamase le chefo e tlase, e fetohile e 'ngoe ea litlhare tsa bohlokoa tsa antibacteria bakeng sa kalafo ea mafu a matla a baktheria.Carbapenems e tsitsitse haholo ho plasmid-mediated extended-spectrum β-lactamases (ESBLs), chromosomes le plasmid-mediated cephalosporinases (AmpC enzymes)^[2].

Tekheniki Parameters

Sebaka se reriloeng	NDM, KPC, OXA-48, IMP le VIM carbapenemases
Mocheso oa polokelo	4℃-30℃
Mofuta oa mohlala	Mehlala ea baktheria e fumanoeng ka mor'a setso
Shelf bophelo	Likhoeli tse 24
Lisebelisoa tse thusang	Ha e hlokehe
Lisebelisoa tse Eketsehileng	Ha e hlokehe
Nako ea ho lemoha	Mehlala ea baktheria e fumanoeng ka mor'a setso
LoD	Mofuta oa NDM:0.15ng/mL Mofuta oa KPC:0.4ng/mL Mofuta oa OXA-48:0.1ng/mL Mofuta oa IMP:0.2ng/mL Mofuta oa VIM:0.3ng/mL.
Hook effect	Bakeng sa NDM, KPC, OXA-48 mofuta oa carbapenemase, ha ho na phello ea hook e fumanehang ka har'a 100ng / mL;bakeng sa IMP, VIM mofuta oa carbapenemase, ha ho na phello ea hook e fumanoang ka har'a mefuta e mengata ea 1μg/mL.