Kankere ea matšoafo e ntse e le phephetso ea bophelo bo botle lefatšeng ka bophara, e behiloe boemong ba bobeli ba kankere e fumanoang hangata. Ka 2020 feela, ho bile le linyeoe tse ncha tse fetang limilione tse 2.2 lefatšeng ka bophara. Kankere ea matšoafo e seng ea lisele tse nyane (NSCLC) e emela ho feta 80% ea li-diagnostic tsohle tsa kankere ea matšoafo, e totobatsang tlhoko e potlakileng ea maano a kalafo a reretsoeng le a sebetsang.
Liphetoho tsa EGFR li hlahile e le lejoe la bohlokoa kalafong ea NSCLC e etselitsoeng motho ka mong. Li-inhibitor tsa tyrosine kinase tsa EGFR (TKIs) li fana ka mokhoa o mocha ka ho thibela matšoao a susumetsang kankere, ho thibela kholo ea hlahala, le ho khothalletsa lefu la lisele tsa kankere—ha e ntse e fokotsa tšenyo liseleng tse phetseng hantle.
Litataiso tse ka sehloohong tsa bongaka, ho kenyeletsoa le NCCN, joale li laela tlhahlobo ea phetoho ea EGFR pele ho qaloa kalafo ea TKI, ho netefatsa hore bakuli ba nepahetseng ba fumana meriana e nepahetseng ho tloha qalong.
Liphetoho tsa EGFR li hlahile e le lejoe la bohlokoa kalafong ea NSCLC e etselitsoeng motho ka mong. Li-inhibitor tsa tyrosine kinase tsa EGFR (TKIs) li fana ka mokhoa o mocha ka ho thibela matšoao a susumetsang kankere, ho thibela kholo ea hlahala, le ho khothalletsa lefu la lisele tsa kankere—ha e ntse e fokotsa tšenyo liseleng tse phetseng hantle.
Litataiso tse ka sehloohong tsa bongaka, ho kenyeletsoa le NCCN, joale li laela tlhahlobo ea phetoho ea EGFR pele ho qaloa kalafo ea TKI, ho netefatsa hore bakuli ba nepahetseng ba fumana meriana e nepahetseng ho tloha qalong.
Ho Hlahisoa Kit ea ho Fumana Liphetoho tsa Gene 29 ea Motho (Fluorescence PCR)
Tlhahlobo e Nepahetseng bakeng sa Liqeto tsa Kalafo tse Tšepahalang
Sete ea ho lemoha EGFR ea Macro & Micro-Test e nolofalletsa ho tsebahatsa ka potlako le ka nepo liphetoho tse 29 tsa bohlokoa ho pholletsa le li-exons 18-21 ka bobeli liphatseng tsa lefutso le tsa metsi - e leng se matlafatsang lingaka ho fetola phekolo ka kholiseho.
Hobaneng U KhethaTeko ea Macro le Micro'sSete ea Teko ea EGFR?
Sete ena e lemoha liphetoho tse 29 tse tloaelehileng tsa liphatsa tsa lefutso tsa EGFR ho li-exons 18-21 ho tsoa lisampoleng tsa lisele kapa mali tsa bakuli ba NSCLC, e akaretsa libaka tsa ho utloa bohloko ba lithethefatsi le ho hanyetsa ho tataisa tšebeliso ea meriana e reretsoeng joalo ka gefitinib le osimertinib.
- 1. Theknoloji e Ntlafaditsweng ya ARMS: ARMS e Ntlafaditsweng ka enhancer e nang le patente bakeng sa ho totobala ho hoholo;
- 2. Ho Ntlafatsa Enzymatic: Ho fokotsa bokamorao ba mofuta wa tlhaho ka ho sila dijo ka enzymatic, ho ntlafatsa ho nepahala ha ho lemoha le ho fokotsa keketseho e sa tobang ka lebaka la bokamorao bo phahameng ba genomic;
- 3. Thibelo ea Thempereichara: E eketsa mekhahlelo e itseng ea mocheso ts'ebetsong ea PCR, e fokotsa ho se lumellane le ho eketsa ho nepahala ha ho lemoha;
- 4. Ho ba le kutlo e phahameng: E lemoha liphetoho tse tlase ho 1% tsa phetoho;
- 5. Ho nepahala ho hoholo: Taolo ea ka hare le enzyme ea UNG ho fokotsa liphetho tse fosahetseng;
- 6. Bokgoni: Liphetho tse nang le sepheo ka hare ho metsotso e 120
- 7. Tšehetso ea Sampole e 'Meli - E ntlafalitsoe bakeng sa lisampole tsa lisele le mali, e fanang ka ho tenyetseha ts'ebetsong ea bongaka
- 8. Ho lumellana ho pharaletseng: E lumellana haholo le lisebelisoa tse kholo tsa PCR 'marakeng;
- 9. Nako ea ho phela: likhoeli tse 12.
Tataiso ea Kalafo ka Boitšepo
Sete ena e thusa ho eketsa diphetho tsa bongaka le ho dula o le ka pele ho kganyetso ka kutlwisiso e tebileng le diphetoho tsa kganyetso.
Atolosa Potefolio ea Hao ea Precision Oncology
Hlahloba mefuta eohle ea rona ea litharollo tsa ho lemoha liphetoho tsa lefutso bakeng sa KRAS, BRAF, ROS1, ALK, BCR-ABL, TEL-AML1, le tse ling—kaofela li etselitsoe ho tšehetsa tlhokomelo e felletseng e tsamaisoang ke biomarker.
Ithute haholoanyane:https://www.mmtest.com/oncology/
Contact our team: marketing@mmtest.com
Nako ea poso: Loetse-23-2025