Antimicrobial resistance (AMR) e fetohile e 'ngoe ea litšokelo tse kholo ka ho fetisisa tsa bophelo bo botle ba sechaba lekholong lena la lilemo, e bakang mafu a fetang limilione tse 1.27 selemo se seng le se seng 'me e kenya letsoho likotsing tse ling tse ka bang limilione tse 5 - koluoa ena e potlakileng ea bophelo bo botle ea lefats'e e hloka hore re nke khato hang-hang.
Beke ena ea Lefatše ea Temoso ea AMR (November 18-24), baetapele ba bophelo bo botle ba lefats'e ba kopana pitsong ea bona:"Nka Hona Joale: Sireletsa Hona Joale ea Rōna, Sireletsa Bokamoso ba Rōna."Sehlooho sena se totobatsa ho potlaka ha ho sebetsana le AMR, e hlokang boiteko bo kopanetsoeng ho pholletsa le bophelo ba batho, bophelo ba liphoofolo le ba tikoloho.
Tšokelo ea AMR e feta meeli ea naha le libaka tsa tlhokomelo ea bophelo. Ho ea ka thuto ea morao-rao ea Lancet, ntle le mehato e sebetsang khahlanong le AMR,Mafu a eketsehang a lefats'e a ka fihla ho limilione tse 39 ka 2050, ha litšenyehelo tsa selemo le selemo tsa ho phekola mafu a hananang le lithethefatsi li lebelletsoe ho nyoloha ho tloha ho liranta tse limilione tse likete tse 66 ho fihlela joale.$ 159 limilione tse likete.
Bothata ba AMR: 'Nete e Tebileng ka morao ho Lipalo
Antimicrobial resistance (AMR) e etsahala ha likokoana-hloko—libaktheria, livaerase, likokoana-hloko le li-fungus—li se li sa arabele meriana e tloaelehileng e thibelang likokoana-hloko. Tlokotsi ena ea bophelo bo botle ea lefats'e e fihlile maemong a tšosang:
-Metsotso e meng le e meng e mehlano, motho a le 1 o bolaoa ke tšoaetso e hananang le lithibela-mafu
-Ka2050AMR e ka fokotsa GDP ea lefats'e ka 3.8%
-96% ea linaha(kakaretso ea 186) ba nkile karolo phuputsong ea 2024 ea lefats'e ea ho latela AMR, e bonts'a kananelo e atileng ea tšokelo ena.
-Likamoreng tsa batho ba kulang haholo libakeng tse ling,ho feta 50% ea li-isolates tsa baktheriabontša ho hanyetsa bonyane lithibela-mafu tse le 'ngoe
Kamoo Likokoana-hloko li Fanang ka Tsona: Mekhoa ea Tšireletso ea Likokoana-hloko
Lithibela-mafu li sebetsa ka ho shebana le lits'ebetso tsa bohlokoa tsa baktheria:
-Tšimoloho ea Lerako la Lisele: Penicillin e sitisa marako a lisele tsa baktheria, e leng ho bakang ho phatloha le lefu
-Tlhahiso ea LiprotheineTetracyclines le macrolides li thibela ribosomes ea baktheria, li emisa tlhahiso ea protheine.
-DNA/RNA Replication: Fluoroquinolones e thibela li-enzyme tse hlokahalang bakeng sa ho ikatisa ha DNA ea baktheria
-Botšepehi ba Membrane ea Lisele: Li-polymyxin li senya lisele tsa baktheria, tse lebisang lefung la sele
-Mekhoa ea metabolicLi-sulfonamides li thibela ts'ebetso ea baktheria ea bohlokoa joalo ka folic acid synthesis
Leha ho le joalo, ka khetho ea tlhaho le liphetoho tsa liphatsa tsa lefutso, libaktheria li hlahisa mekhoa e mengata ea ho hanela lithibela-mafu, ho kenyelletsa le ho hlahisa li-enzyme tse sa sebetseng, ho fetola lipakane tsa lithethefatsi, ho fokotsa ho bokella lithethefatsi, le ho etsa li-biofilms.
Carbapenemase: The "Super Weapon" Maqakabetsing a AMR
Har'a mekhoa e sa tšoaneng ea ho hanyetsa, tlhahiso eali-carbapenemase amehang ka ho khetheha. Li-enzyme tsena li hydrolyze lithibela-mafu tsa carbapenem-tseo hangata li nkoang e le "litlhare tsa ho qetela". Li-carbapenemase li sebetsa e le "lihlomo tse phahameng" tsa baktheria, li senya lithibela-mafu pele li kena liseleng tsa baktheria. Libaktheria tse jereng li-enzyme tsena-joalokaKlebsiella pneumoniaeleAcinetobacter baumannii—e ka phela le ho ikatisa le ha e pepesehetse lithibela-mafu tse matla ka ho fetisisa.
Ho makatsang le ho feta, liphatsa tsa lefutso tse kenyelletsang li-carbapenemase li fumaneha linthong tsa liphatsa tsa lefutso tse ka fetisang lipakeng tsa mefuta e fapaneng ea libaktheria.ho potlakisa ho ata lefatšeng ka bophara ha libaktheria tse hanyetsanang le lithethefatsi tse ngata.
Tlhahlobos: Mohala oa Pele oa Tšireletso ho Taolo ea AMR
Litlhahlobo tse nepahetseng, tse potlakileng li bohlokoa ho loantšeng AMR. Ho tsebahatsa libaktheria tse hanyetsanang ka nako ho ka:
-Tataisa phekolo e nepahetseng, ho qoba tšebeliso e sa sebetseng ea lithibela-mafu
-Ho kenya tšebetsong mehato ea taolo ea tšoaetso ho thibela phetiso ea libaktheria tse itoanelang
-Sheba mekhoa ea ho hanyetsa ho tsebisa liqeto tsa bophelo ba sechaba
Litharollo tsa Rōna: Lisebelisoa tse Ncha bakeng sa Ntoa ea Precision AMR
E le ho sebetsana le phephetso e ntseng e eketseha ea AMR, Macro & Micro-Test e hlahisitse lisebelisoa tse tharo tse ncha tsa ho lemoha carbapenemase tse finyellang litlhoko tse fapaneng tsa kliniki, ho thusa bafani ba tlhokomelo ea bophelo ka potlako le ka nepo ho khetholla libaktheria tse hanyetsanang le ho etsa bonnete ba ho kenella ka nako le liphello tse ntlafetseng tsa mokuli.
1. Carbapenemase Detection Kit (Colloidal Gold)
E sebelisa theknoloji ea khauta ea colloidal ho fumana carbapenemase e potlakileng, e tšepahalang. E loketse lipetlele, litleliniki, esita le tšebeliso ea lapeng, ho nolofatsa mokhoa oa ho hlahloba ka ho nepahala ho phahameng.
Melemo ea mantlha:
-Tlhaloso e Pharalletseng: Ka nako e le 'ngoe e supa mefuta e mehlano ea ho hanyetsa—NDM, KPC, OXA-48, IMP, le VIM
-Liphetho tse potlakileng: E fana ka liphetho ka hareMetsotso e 15, ka potlako haholo ho feta mekhoa ea setso (matsatsi a 1-2)
-Mosebetsi o Bonolo: Ha ho lisebelisoa tse rarahaneng kapa koetliso e khethehileng e hlokahalang, e loketseng litlhophiso tse fapaneng
-Ho Nepaha ha Phahameng: 95% ea kutlo e se nang matšoao a fosahetseng ho tsoa ho libaktheria tse tloaelehileng joalo ka Klebsiella pneumoniae kapa Pseudomonas aeruginosa
2. Carbapenem Resistance Gene Detection Kit (Fluorescence PCR)
E etselitsoe bakeng sa tlhahlobo e tebileng ea liphatsa tsa lefutso tsa khanyetso ea carbapenem. E loketse bakeng sa tlhahlobo e felletseng ea lilaboratori tsa kliniki, ho fana ka tlhahlobo e nepahetseng ea liphatsa tsa lefutso tse ngata tsa ho hanyetsa carbapenem.
Melemo ea mantlha:
-Flexible Sampling: Ho lemoha ka ho toba ho tlohalikolone tse hloekileng, sekhohlela, kapa li-swabs tsa rectal-ha ho na setsohlokahala
-Phokotso ea Litšenyehelo: E lemoha liphatsa tsa lefutso tse tšeletseng tsa khanyetso (NDM, KPC, OXA-48, OXA-23) IMP, le VIM tekong e le 'ngoe, ho felisa liteko tse sa hlokahaleng
-Kutloelo-bohloko e Phahameng le ho Khetheha: Moeli oa ho sibolla o tlase ho 1000 CFU/mL, ha ho na cross-reactivity le mefuta e meng ea ho hanyetsa joalo ka CTX, mecA, SME, SHV, le TEM
-Ho lumellana ho pharaletseng: E lumellana leMohlala-ho-AraboAIO 800 ea POCT ea limolek'hule ka botlalo le lisebelisoa tsa mantlha tsa PCR
3. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa le Resistance Genes Multiplex Detection Kit (Fluorescence PCR)
Setsi sena se kopanya boitsebiso ba baktheria le mekhoa ea ho hanyetsa e amanang le eona hore e be mokhoa o le mong o hlophisitsoeng bakeng sa tlhahlobo e nepahetseng.
Melemo ea mantlha:
-Tlhaloso e Pharalletseng: E tsebahatsa ka nako e le nngwelikokoana-hloko tse tharo tsa bohlokoa tsa baktheria-Klebsiella pneumoniae, Acinetobacter baumannii, le Pseudomonas aeruginosa-'me e lemoha mefuta e mene ea bohlokoa ea carbapenemase (KPC, NDM, OXA48, le IMP) tekong e le 'ngoe.
-Boikutlo bo Phahameng: E khona ho bona DNA ea baktheria maemong a tlase ho 1000 CFU/mL
-E tšehetsa Qeto ea Clinical: E thusa ho khetha liphekolo tse sebetsang hantle tsa lithibela-mafu ka ho tsebahatsa mefuta e hanyetsanang le mafu
-Ho lumellana ho pharaletseng: E lumellana leMohlala-ho-AraboAIO 800 ea POCT ea limolek'hule ka botlalo le lisebelisoa tsa mantlha tsa PCR
Lisebelisoa tsena tsa ho lemoha li fana ka litsebi tsa tlhokomelo ea bophelo lisebelisoa tsa ho sebetsana le AMR maemong a fapaneng-ho tloha tekong ea tlhokomelo e potlakileng ho ea ho tlhahlobo e qaqileng ea liphatsa tsa lefutso-ho netefatsa ho kenella ka nako le ho fokotsa ho ata ha libaktheria tse hanyetsanang.
Ho loantša AMR le Precision Diagnostics
Ho Macro & Micro-Test, re fana ka lisebelisoa tsa tlhahlobo tse tsoetseng pele tse matlafatsang bafani ba tlhokomelo ea bophelo bo botle ka temohisiso e potlakileng, e tšepahalang, e nolofalletsang liphetoho tsa kalafo ka nako le taolo e sebetsang ea ts'oaetso.
Joalo ka ha ho totobalitsoe Bekeng ea Tlhokomeliso ea AMR ea Lefatše, likhetho tsa rona kajeno li tla tsebahatsa bokhoni ba rona ba ho sireletsa meloko ea hajoale le e tlang ho tsoa tšokelong ea ho hanyetsa likokoana-hloko.
Eba karolo ea ntoa khahlanong le ho hanyetsa likokoana-hloko - bophelo bo bong le bo bong bo pholositsoeng ke litaba.
For more information, please contact: marketing@mmtest.com
Nako ea poso: Nov-19-2025