Tlhahlobo eaClassic Research Pampiri
Respiratory Syncytial Virus (RSV) le Human Metapneumovirus (HMPV) li toho likokoana-hloko tse amanang haufi-ufi ka hare hoPneumoviridaelelapatse ferekanngoang khafetsa maemong a ts'oaetso e matla ea ho hema ho bana. Le ha liphatlalatso tsa bona tsa bongaka li kopana, lintlha tse lebelletsoeng ho lebela (2016-2020) ho tsoa lipetleleng tsa bana tse 7 tsa US - tse kenyelletsang bakuli ba 8,605 - li senola phapang e kholo lipakeng tsa bona tse kotsing e kholo, ho teba ha mafu, le taolo ea bongaka. Phuputso ena e sebelisitse moralo o sebetsang, o lebelletsoeng o nang le pokello e hlophisitsoeng ea nasopharyngeal swab le tlhahlobo ea livaerase tse 8 tsa phefumoloho, e fana ka papiso ea pele e kholo, ea nnete ea lefats'e bakeng sa lingaka tsa bana. Ka ho hlahloba litekanyetso tsa ho kena sepetlele, ho amoheloa ha ICU, tšebeliso ea mochine oa moea, le ho lula nako e telele sepetlele (≥3 matsatsi), e theha motheo oa bohlokoa oa lefu la seoa pele ho nako ea nako ea liente tse ncha tsa RSV (mohlala, liente tsa bakhachane, li-anti-monoclonal tse tšoarellang nako e telele) le ho theha moralo oa tsoelo-pele oa HMPV bakeng sa bokamoso.
Ho Fumana lintlha tsa Bohlokoa 1: Litaba tse ikhethileng tse nang le kotsi e kholo
-RSV e ama haholo bana ba banyenyane:Nako e bohareng ea ho kena sepetlele e ne e le likhoeli tse 7 feela, 'me 29.2% ea bakuli ba amoheloang e le masea (likhoeli tse 0-2). RSV ke sesosa se ka sehloohong sa ho kena sepetlele ho masea a ka tlaase ho likhoeli tse 6, ka matla a amanang le lilemo.
-HMPV e shebane le bana ba seng ba hōlile le ba nang le mafu a tšoanang:Nako e bohareng ea ho kena sepetlele e ne e le likhoeli tse 16, ka tšusumetso e kholo ho bana ba ka holimo ho selemo se le seng. Ka ho hlakileng, ho ata ha maemo a bophelo bo botle (mohlala, pelo, methapo ea kutlo, ho phefumoloha) ho ne ho feta habeli ho bakuli ba HMPV (26%) ha ho bapisoa le bakuli ba RSV (11%), ba totobatsang ts'oaetso ea bona e phahameng.
Setšoantšo sa 1. Kabo ea lilemo tsa maeto a ED le lipetlelee amanang le RSV kapa HMPV
ho bana ba ka tlase ho lilemo tse 18.
Ho Fumana Ntho ea Bohlokoa 2: Ho Fapanya Litlhahiso tsa Tleliniki
-RSV e bonahala ka matšoao a tlase a phefumoloho a tlase:E amahanngoa haholo le bronchiolitis (76.7% ea linyeoe tsa sepetlele). Lipontšo tsa bohlokoa li kenyelletsaho khutlisa lebota la sefuba (76.9% bakuli ba bakuli; 27.5% ED)letachypnea (91.8% ea bakuli; 69.8% ED), ka bobeli hangata ho feta ho HMPV.
-HMPV e hlahisa kotsi e phahameng ea feberu le pneumonia:Pneumonia e ile ea fumanoa ho 35.6% ea bakuli ba HMPV ba sepetlele-habeli tekanyo ea RSV.Feberu e ne e le tšobotsi e atileng haholo (83.6% bakuli ba bakuli; 81% ED). Le hoja matšoao a ho hema a kang ho hema le tachypnea a etsahala, hangata ha a matla haholo ho feta a RSV.
Setšoantšo sa 2.Litšobotsi tsa papiso le klinikinete horeea RSV khahlano le HMPV ho bana ba ka tlase ho lilemo tse 18.
Kakaretso: RSVHangata e baka mafu a matla ho masea a manyenyane, a khetholloang ke khatello e kholo ea ho hema (ho hema, ho kheloha) le bronchiolitis.HMPVhangata e ama bana ba seng ba hōlile ba nang le mafu a tšoaetsanoang, e hlahisoang ke feberu e hlahelletseng, e na le kotsi e kholo ea ho tšoaroa ke nyumonia, 'me hangata e baka karabelo e pharaletseng ea ho ruruha.
Ho Fumana Ntho ea Bohlokoa 3: Lipaterone tsa Sehla ke tsa Bohlokoa
-RSV e na le tlhoro ea pele, e ka lebelloang esale pele:Ts'ebetso ea eona e tsepamisitsoe haholo, hangata e phahama lipakengPulungoana le Pherekhong, ho etsa hore e be tšokelo e ka sehloohong ea kokoana-hloko ho masea nakong ea hoetla le mariha.
-HMPV e nyoloha hamorao ka phapang e kholo:Nako ea eona e fihla hamorao, hangata e fihla sehlohlolongMarch le April, 'me e bontša phapang ea bohlokoa ea selemo le selemo le ea libaka, hangata e hlahang e le "leqhubu la bobeli" ka mor'a hore RSV e fokotsehe.
Setšoantšo sa 3.Ka kakaretso le sebaka se ikhethileng PCR positivelitefiso tsa RSV le HMPV har'a bana ba ka tlase ho lilemo tse 18 ba nang le tšoaetso e matla ea ho hema (ARI) -e amanang le maeto a ED le lipetlele.
Thibelo le Tlhokomelo: Leano la Ts'ebetso le Thehiloeng ho Bopaki
-Thibelo ea RSV:Mekhoa ea thibelo e se e fumaneha. Ka 2023, US FDA e ile ea amohela antibody ea nako e telele ea monoclonal (Nirsevimab), e ka sireletsang masea likhoeling tsa bona tsa pele tse 5. Ho feta moo, ente ea RSV ea bakhachane e fetisetsa li-antibodies ho masea a sa tsoa tsoaloa.
-Thibelo ea HMPV:Hajoale ha ho na meriana e thibelang e amohetsoeng. Leha ho le joalo, bakuli ba 'maloa ba enteng (mohlala, ente e kopaneng ea RSV/HMPV ea AstraZeneca) ba litekong tsa bongaka. Batsoali ba eletsoa ho lula ba tseba ka lintlafatso tse tsoang ho balaoli ba bophelo bo botle ba sechaba.
Batla Tlhokomelo ea Bongaka hang-hang bakeng sa "Lifolakha tse Khubelu" tsena:
-Feberu ho masea:Thempereichara ≥38°C (100.4°F) ho lesea lefe kapa lefe le ka tlase ho likhoeli tse 3.
-Sekhahla se Phahameng sa ho Phefumoloha:Ho phefumoloha ho feta ho phefumoloha ha 60 ka motsotso bakeng sa masea likhoeli tse 1-5, kapa ho phefumoloha ha 40 ka motsotso bakeng sa bana ba lilemo tse 1-5, ho bontša hore ho na le bothata ba ho hema.
-Phaello e Tlase ea Oksijene:Oxygen saturation (SpO₂) e oela ka tlase ho 90%, e leng letšoao le mahlonoko la boloetse bo matla bo hlokometsoeng ho 30% ea RSV le 32.1% ea linyeoe tsa HMPV tsa sepetlele thutong.
-Lethargy kapa Mathata a ho Fepa:Ho khathala ho hlokomelehang kapa phokotso ea lebese le nooang ka ho feta karolo e le 'ngoe ho tse tharo nakong ea lihora tse 24, e ka bang selelekela sa ho felloa ke metsi 'meleng.
Le hoja e fapane le lefu la seoa le tlhahiso ea meriana, ho khetholla ka nepo pakeng tsa RSV le HMPV sebakeng sa tlhokomelo ho ntse ho le thata. Ho feta moo, tšokelo ea bongaka e fetela ka nģ'ane ho livaerase tsena tse peli, 'me likokoana-hloko tse kang ntaramane A le bongata ba likokoana-hloko tse ling tsa kokoana-hloko le baktheria ka nako e le 'ngoe li beha bophelo ba batho kotsing. Ka hona, tlhahlobo ea nako e nepahetseng le e nepahetseng ea etiological ke ea bohlokoa bakeng sa taolo e nepahetseng ea ts'ehetso, ho itšehla thajana, le kabo e nepahetseng ea lisebelisoa.
Re Tseba ka AIO800 + 14-Pathogen Combined Detection Kit (Fluorescence PCR)(NMPA, CE, FDA, SFDA e amohetsoe)
Ho fihlela tlhoko ena, theEudemon™ AIO800 Sistimi ea ho Khetholla Nucleic Acid ka Botlalo, e kopantsoe le a14-pathogen phefumoloho phanele, e fana ka tharollo ea phetoho - ho fana ka 'nete"mohlala ka hare, araba"diagnostics ka metsotso e 30 feela.
Teko ena e akaretsang ea ho phefumoloha e lemohas bobeli livaerase le libaktheriaho tsoa ho sampole e le 'ngoe, e nolofalletsang bafani ba bophelo bo botle ba pele ho etsa liqeto tsa kalafo tse itšepa, ka nako, le tse lebisitsoeng ho tsona.
Lintlha tsa Bohlokoa tsa Sisteme tse Bohlokoa ho Bareki ba Hao
Mokhoa oa ho sebetsa ka botlalo
Nako e ka tlase ho metsotso e 5. Ha ho hlokahale basebetsi ba nang le tsebo ea limolek'hule.
- Liphetho tse potlakileng
Nako ea ho fetola metsotso e 30 e tšehetsa maemo a potlakileng a kliniki.
- 14Ho fumanoa ha Pathogen Multiplex
Tlhahiso ea nako e le 'ngoe ea:
Livaerase:COVID-19, Influenza A & B,RSV,Adv,hMPV, Rhv,Parainfluenza mefuta I-IV, HBoV,EV, CoV
Baktheria:MP,Cpn, SP
-Li-reagents tsa Lyophilized Tse Tsitseng Mocheng oa Kamore (2–30°C)
E nolofatsa polokelo le lipalangoang, e felisa ho itšetleha ka ketane e batang.
Sistimi e matla ea Thibelo ea Tšilafalo
Mehato ea 11-layer e khahlanong le tšilafalo e kenyelletsang sterilization ea UV, filtration ea HEPA, le ts'ebetso ea cartridge e koetsoeng, jj.
Ho tseba ka potlako, ka botlalo pathogen ke motheo oa taolo ea sejoale-joale ea mafu a phefumoloho a bana. Sistimi ea AIO800, e nang le phanele ea PCR e ikemetseng ka botlalo, metsotso e 30, e fana ka tharollo e sebetsang bakeng sa litlhophiso tsa pele. Ka ho nolofalletsa ho lemoha pele le ho nepahala ha RSV, HMPV, le likokoana-hloko tse ling tsa bohlokoa, e matlafatsa baoki ho etsa liqeto tse lebisitsoeng tsa phekolo, ho ntlafatsa tšebeliso ea lithibela-mafu, le ho kenya ts'ebetsong taolo e sebetsang ea tšoaetso-qetellong e ntlafatsa tlhokomelo ea mokuli le tlhokomelo ea bophelo bo botle.
#RSV #HMPV #Ka potlako # Boitsebiso #Ho phefumoloha #Pathogen # Mohlala-ho-Karabo#MacroMicroTest
Nako ea poso: Dec-02-2025