Bophelo bo botle ba ho ba le bana bo tsamaisana le potoloho ea bophelo bohle ba rona, e neng e nkuoa e le e 'ngoe ea matšoao a bohlokoa a bophelo bo botle ba batho ke WHO.Ho sa le joalo, "bophelo ba ho ba le bana bakeng sa bohle" bo amoheloa e le Sepheo sa UN sa Ntlafatso ea Moshoelella.E le karolo ea bohlokoa ea bophelo bo botle ba ho ba le bana, ts'ebetso ea tsamaiso ea pelehi, mekhoa le mesebetsi e ameha ho monna e mong le e mong.
01 Likotsiofmafu a ho tsoala
Mafu a tšoaetsanoang ke tšisinyeho ea botona le botšehali ke tšokelo e kholo ho bophelo bo botle ba botona le botšehali, bo bakang ho hloka thari ho hoo e ka bang 15% ea bakuli.E bakoa haholo ke Chlamydia Trachomatis, Mycoplasma Genitalium le Ureaplasma Urealyticum.Leha ho le joalo, hoo e ka bang 50% ea banna le 90% ea basali ba nang le ts'oaetso ea tšoaetso ea botona kapa botšehali ba na le subclinical kapa asymptomatic, e lebisang ho thibelo le taolo ea phetiso ea likokoana-hloko e hlokomolohuoa.Ho hlahlojoa ka nako le ka katleho ha mafu ana ka hona ho fana ka tikoloho e ntle ea bophelo bo botle ba ho ba le bana.
Chlamydia Trachomatis Infection (CT)
Chlamydia trachomatis urogenital tract infection e ka baka urethritis, epididymitis, prostatitis, proctitis le ho hloka thari ho banna hape e ka baka cervicitis, urethritis, lefu la ho ruruha ha pelvic, adnexitis, le ho hloka thari ho basali.Ka nako e ts'oanang, tšoaetso ea Chlamydia trachomatis ho basali ba bakhachane e ka lebisa ho phatloheng ha lera pele ho nako, ho tsoala lesea le shoeleng, ho ntša mpa ka tšohanyetso, endometritis ka mor'a ho ntša mpa le liketsahalo tse ling.Haeba e sa phekoloe ka katleho ho basali ba bakhachane, e ka fetisetsoa ho masea a sa tsoa tsoaloa ka ho toba, a baka ophthalmia, nasopharyngitis le pneumonia.Tšoaetso e sa foleng le e pheta-phetoang ea genitourinary Chlamydia trachomatis e atisa ho fetoha mafu, a kang cervical squamous cell carcinoma le AIDS.
Neisseria Gonorrhoeae Infection (NG)
Lipontšo tsa kliniki tsa Neisseria gonorrhoeae tšoaetso ea pampitšana ea urogenital ke urethritis le cervicitis, 'me matšoao a eona a tloaelehileng ke dysuria, ho ntša metsi khafetsa, ho potlaka, dysuria, mucus kapa purulent discharge.Haeba e sa phekoloe ka nako, gonococci e ka kena ka urethra kapa ea hasana ho ea holimo ho tloha molomong oa pōpelo, ea baka prostatitis, vesiculitis, epididymitis, endometritis le salpingitis.Maemong a matla, e ka baka sepsis ea gonococcal ka ho phatlalatsoa ha hematogenous.Mucosal necrosis e bakang squamous epithelium kapa tokiso ea linama tse hokahaneng e ka lebisa ho urethral stricture, vas deferens le tubal narrowing kapa esita le atresia esita le ho ectopic pregnancy le ho hloka thari ho banna le basali.
Tšoaetso ea Ureaplasma Urealyticum (UU)
Hangata ureaplasma urealyticum e na le likokoana-hloko ka har'a urethra ea banna, letlalo la setho sa botona le ka botšehaling ba mosali.E ka baka tšoaetso ea moroto le ho hloka thari tlas'a maemo a itseng.Lefu le atileng haholo le bakoang ke ureaplasma ke nongonococcal urethritis, e etsang karolo ea 60 lekholong ea urethritis e seng baktheria.E ka boela ea baka prostatitis kapa epididymitis ho banna, vaginitis ho basali, cervicitis, tsoalo ea pele ho nako, boima ba 'mele bo tlaase, hape e ka baka tšoaetso ea tsamaiso ea methapo ea ho hema le bohareng ba masea a sa tsoa tsoaloa.
Tšoaetso ea Herpes Simplex Virus (HSV)
Herpes simplex virus, kapa herpes, e arotsoe ka lihlopha tse peli: herpes simplex kokoana-hloko ea mofuta oa 1 le herpes simplex kokoana-hloko ea mofuta oa 2. Herpes simplex kokoana-hloko ea mofuta oa 1 e baka oral herpes haholo-holo ka ho kopana le molomo ho ea molomong, empa hape e ka baka herpes ea thobalano.Mofuta oa 2 oa kokoana-hloko ea Herpes simplex ke tšoaetso ea thobalano e bakang herpes ea thobalano.Genital herpes e ka ipheta hape 'me ea ba le tšusumetso e kholo ho bophelo bo botle le kelello ea bakuli.E ka boela ea tšoaetsa masea a sa tsoa tsoaloa ka placenta le kanale ea tsoalo, e leng se lebisang tšoaetsong ea tsoalo ea masea a sa tsoa tsoaloa.
Mycoplasma Genitalium Infection (MG)
Mycoplasma genitalium ke sephedi se senyane se tsebahalang se ikatisang se nang le 580kb feela mme se fumanwa haholo ho batho le diphoofolo tse ngata.Ho bacha ba kopanelang liphate, ho na le kamano e matla pakeng tsa ho se tloaelehe ha pampitšana ea urogenital le Mycoplasma genitalium, ho fihlela ho 12% ea bakuli ba nang le matšoao ba nang le tšoaetso ea Mycoplasma genitalium.Ntle ho moo, pepole e tšoaelitsoeng Mycoplasma Genitalium e ka boela ea fetoha urethritis e seng gonococcal le prostatitis e sa foleng.Mycoplasma genitalium tšoaetso ke sesosa se ikemetseng sa ho ruruha ha molomo ho basali 'me se amahanngoa le endometritis.
Mycoplasma Hominis Infection (MH)
Mycoplasma hominis tšoaetso ea pampitšana genitourinary ka baka mafu a kang non-gonococcal urethritis le epididymitis ho banna.E iponahatsa e le ho ruruha ha tsamaiso ea ho ikatisa ho basali ho hasana ho lebisitsoe molomong oa popelo, 'me bothata bo tloaelehileng ke salpingitis.Endometritis le lefu la ho ruruha ha pelvic li ka etsahala ho palo e nyenyane ea bakuli.
02Tharollo
Macro & Micro-Test e ikakhetse ka setotsoana ho nts'etsopele ea li-reagents tsa ts'oaetso ea mafu a urogenital, 'me e hlahisitse lisebelisoa tse amanang le ho lemoha (Isothermal Amplification Detection method) ka tsela e latelang:
03 Tlhaloso ea Sehlahisoa
| Lebitso la Sehlahiswa | Tlhaloso |
| Chlamydia Trachomatis Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification) | 20 liteko / kit 50 liteko / kit |
| Neisseria Gonorrhoeae Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification) | 20 liteko / kit 50 liteko / kit |
| Ureaplasma Urealyticum Nucleic Acid Detection Kit(Enzymatic Probe Isothermal Amplification) | 20 liteko / kit 50 liteko / kit |
| Herpes Simplex Virus Type 2 Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification) | 20 liteko / kit 50 liteko / kit |
04 Amelemo
1. Taolo ea ka hare e kenngoa tsamaisong ena, e ka shebellang ka botlalo ts'ebetso ea liteko le ho netefatsa boleng ba teko.
2. Mokhoa oa Isothermal Amplification Detection nako e khuts'oane ea teko, 'me sephetho se ka fumanoa nakong ea metsotso e 30.
3. Ka Macro & Micro-Test Sample Release Reagent le Macro & Micro-Test Automatic Nucleic Acid Extractor (HWTS-3006), e bonolo ho sebetsa le e loketseng maemo a sa tšoaneng.
4. Boikutlo bo phahameng: LoD ea CT ke 400copies / mL;LoD ea NG ke 50 pcs / mL;LoD ea UU ke 400copies/mL;LOD ea HSV2 ke likopi tse 400/mL.
5. Boemo bo phahameng: ha ho na cross-reactivity le likokoana-hloko tse ling tse amanang le tšoaetso (joaloka syphilis, genital warts, chancroid chancre, trichomoniasis, hepatitis B le AIDS).
Litšupiso:
[1] LOTTI F,MAGGI M.Ho se sebetse ka thobalano le ho hloka thari ha banna [J].NatRev Urol,2018,15(5):287-307.
[2] CHOY JT,EISENBERG ML.Ho hloka thari ha banna e le fensetere ea bophelo bo botle[J].Fertil Steril,2018,110(5):810-814.
[3] ZHOU Z,ZHENG D,WU H,et al.Epidemiology of infertility in China:phuputso e thehiloeng ho palo ea baahi[J].BJOG,2018,125(4):432-441.
Nako ea poso: Nov-04-2022