Ke MyEgenOO Bonolomia (CML) ke lefu le utloisang bohloko la hematopoigic. Bakuli ba fetang 95% ba bakuli ba CMl ba na le phililadel ea Philadephia (ph) libakeng tsa mali a bona. 'Me sethala sa BR-ABL se thehoa ka ho fetisoa lipakeng tsa Abl Proto-ONCOGene (ABSOGE) ea chromosome 22 (22q11). Timo ea eona ea tumo e ile ea khangoa ke tyrosine knase (tk) ho phahamisa litsela tsa eona tsa konoko, 'me ka tsela e molemo ka tsela eo. ketsahalo ea CML.
BR-ABL Fusion Chan, e leng bohlokoa ho nts'etsopele ea CML, e sebeletsa e le mofuta oa tlhahlobo ea bongaka ea cml. Ho lemoha ha eona ho thusa ho hlokomela mokuli'Karabelo ea ho kuku ea thrine ninase inhibitors
Motho BR-ABLLi-fusion tsa Throlho tloha ho tlhahlobo ea macro le pero ea macro e kenya tlhahlobo ea tlhahlobo ea cml le ho ba tataisang kalafo e lebisitsoeng ho ntlafatsa maano a kalafo ea maano a matheba a sebetsang a mokuli abl fusion gene, e lengkebohlokoaHo nts'etsopele ea CML,e sebeletsa e le mofuta oa senotlolo sa tlhahloboofCml. Ho lemoha ha eona ho thusa hoShebellamokuli'sKarabelo ho throrine knase inhibitors (tkis)mmee rekema leukemia remmuso, e lengBohlokoato E sebetsa hantleCmlTsamaiso ea Mamello.
CR-BR-ABL FONY TEMON TRICE TRICE LITRONS ho tloha ho liteko tsa macro, e thusaCmlTlhahlobo ea TlhahlobommeTataisoTlhahlobo e Khopotsoeng ea KholotoOptimizemaano a kalafo bakeng sa taolo e atlehileng ea mokuli.
Ba utloisisangDetection:Ka nako e tšoanangHo lemohabakeng sa3Disconing Cusion Comney - P210, P190, P230)bakeng saPhatlalatso e pharalletseng leThibelo ho tsoa ho linyeoe tse lahlehileng;
Mohopolo o phahameng:Mofuta oa metsi o bona liphatsa tsa mafuraka lodea kopi ea 1000 / ML,mme mofuta oa lyophilizedof 500 likopi / ml;
E ntle haholoACCURACY: I-hang-hangTaolo'me unzzyme ea ho thibela tse ntle tsa bohata&Libete;
Ts'ebetso e bonolo le katleho:Ts'ebetso e koetsoeng,mahala ho lihlahisoaHo sebetsa ka poso,mmeHo lemohaka hareMetsotso e 60bakeng saLiphetho tsa sepheo le tse tšepahalang;
HapeLikhetho:Mefuta ea metsi le Lyophili e behiloe bakeng sa likhetho tsa bareki;
Kamohelo:E lumellana le litsamaiso tse ngata tsa pac bakeng sa ho fumana chelete e ngata.
Ba utloisisangDetection:Ka nako e tšoanangHo lemohabakeng sa3Disconing Cusion Comney - P210, P190, P230)bakeng saPhatlalatso e pharalletseng leThibelo ho tsoa ho linyeoe tse lahlehileng;
Mohopolo o phahameng:Mofuta oa metsi o bona liphatsa tsa mafuraka lodea kopi ea 1000 / ML,mme mofuta oa lyophilizedof 500 likopi / ml;
E ntle haholoACCURACY: I-hang-hangTaolo'me unzzyme ea ho thibela tse ntle tsa bohata&Libete;
Ts'ebetso e bonolo le katleho:Ts'ebetso e koetsoeng,mahala ho lihlahisoaHo sebetsa ka poso,mmeHo lemohaka hareMetsotso e 60bakeng saLiphetho tsa sepheo le tse tšepahalang;
HapeLikhetho:Mefuta ea metsi le Lyophili e behiloe bakeng sa likhetho tsa bareki;
Kamohelo:E lumellana le litsamaiso tse ngata tsa pac bakeng sa ho fumana chelete e ngata.
Nako ea poso: Mots'eanong-16-2024