Selemo se seng le se seng ka la 17 Mmesa ke Letsatsi la Lefatše la Kankere.
01 Kakaretso ea Ketsahalo ea Kankere ea Lefatše
Lilemong tsa morao tjena, ka keketseho e tsoelang pele ea bophelo ba batho le khatello ea kelello, palo ea lihlahala le eona e ntse e eketseha selemo le selemo.
Lihlahala tse kotsi (kankere) li fetohile tse ling tsa mathata a maholo a bophelo bo botle a sokelang bophelo bo botle ba baahi ba Machaena haholo.Ho ea ka lintlha tsa morao-rao tsa lipalo-palo, lefu la lihlahala tse kotsi le etsa 23,91% ea lisosa tsohle tsa lefu har'a baahi, 'me liketsahalo le lefu la lihlahala tse kotsi li' nile tsa tsoela pele ho phahama lilemong tse leshome tse fetileng.Empa kankere ha e bolele "kahlolo ea lefu."Mokhatlo oa Lefatše oa Bophelo o ile oa bontša ka ho hlaka hore ha feela e ka fumanoa kapele, 60% -90% ea kankere e ka phekoleha!Karolo ea boraro ea mofetše e ka thibeloa, karolo ea boraro ea mofetše e a phekoleha, 'me karolo ea boraro ea mofetše e ka phekoloa ho lelefatsa bophelo.
02 Hlahala ke eng
Hlahala e bua ka setho se secha se entsoeng ke ho ata ha lisele tsa lisele tsa sebakeng seo tlas'a ketso ea lintlha tse sa tšoaneng tsa tumorigenic.Boithuto bo fumane hore lisele tsa tumor li na le liphetoho tsa metabolic tse fapaneng le lisele tse tloaelehileng.Ka nako e ts'oanang, lisele tsa hlahala li ka ikamahanya le liphetoho tikolohong ea metabolic ka ho fetoha lipakeng tsa glycolysis le oxidative phosphorylation.
03 Phekolo ea Kankere e Ikemetseng
Kalafo ea mofets'e ka bomong e ipapisitse le tlhaiso-leseling ea tlhahlobo ea lefutso le liphetho tsa lipatlisiso tsa bongaka tse thehiloeng bopaking.E fana ka motheo oa hore bakuli ba fumane moralo o nepahetseng oa phekolo, o fetohileng mokhoa oa tsoelo-pele ea kajeno ea bongaka.Liphuputso tsa bongaka li tiisitse hore ka ho lemoha phetoho ea liphatsa tsa lefutso tsa li-biomarker, mofuta oa SNP typing, gene le boemo ba eona ba protheine ho lisampole tsa likokoana-hloko tsa bakuli ba hlahala ho bolela esale pele katleho ea lithethefatsi le ho hlahloba tsoelo-pele, le ho tataisa phekolo ea motho ka mong, e ka ntlafatsa katleho le ho fokotsa liphello tse mpe. reactions , ho khothalletsa tšebeliso e utloahalang ea lisebelisoa tsa bongaka.
Teko ea limolek'hule bakeng sa mofetše e ka aroloa ka mefuta e 3 ea mantlha: tlhahlobo, lefutso le kalafo.Teko ea kalafo e bohareng ba seo ho thoeng ke "phekolo ea kalafo" kapa moriana o ikhethileng, 'me li-antibodies tse ngata le li-inhibitors tse nyane tsa molek'hule tse ka lebisang liphatsa tsa lefutso tse khethehileng tsa tumor le litsela tsa matšoao li ka sebelisoa kalafong ea lihlahala.
Phekolo e lebisitsoeng ho limolek'hule ea lihlahala e shebana le limolek'hule tse tšoaeang lisele tsa tumor mme e kenella ts'ebetsong ea lisele tse nang le mofetše.Phello ea eona e haholo-holo liseleng tsa hlahala, empa e na le phello e fokolang liseleng tse tloaelehileng.Li-receptors tsa tumor growth factor, limolek'hule tsa transduction signal, cell cycle proteins, apoptosis regulators, proteolytic enzymes, vascular endothelial growth factor, joalo-joalo kaofela li ka sebelisoa e le sepheo sa molek'hule bakeng sa phekolo ea hlahala.Ka la 28 Tšitoe 2020, "Mehato ea Tsamaiso ea Ts'ebeliso ea Tleliniki ea Lithethefatsi tsa Antineoplastic (Trial)" e fanoeng ke Khomishene ea Naha ea Bophelo le Bongaka e bontšitse ka ho hlaka hore: Bakeng sa lithethefatsi tse nang le sepheo se hlakileng sa lefutso, molao-motheo oa ho li sebelisa o tlameha ho lateloa kamora tekolo ea liphatsa tsa lefutso.
04 Teko ea lefutso e lebisitsoeng ho hlahala
Ho na le mefuta e mengata ea phetoho ea liphatsa tsa lefutso ka har'a lihlahala, 'me mefuta e fapaneng ea phetoho ea liphatsa tsa lefutso e sebelisa lithethefatsi tse lebisitsoeng tse fapaneng.Ke feela ka ho hlakisa mofuta oa phetoho ea liphatsa tsa lefutso le ho khetha ka nepo phekolo ea meriana e lebisitsoeng ho bakuli ba ka ruang molemo.Mekhoa ea ho lemoha limolek'hule e ne e sebelisoa ho lemoha phapang ea liphatsa tsa lefutso tse amanang le lithethefatsi tse atisang ho lebisoa lihlahala.Ka ho sekaseka phello ea mefuta e fapaneng ea liphatsa tsa lefutso mabapi le katleho ea lithethefatsi, re ka thusa lingaka ho theha leano la kalafo le nepahetseng ka ho fetisisa.
05 Tharollo
Macro & Micro-Test e thehile letoto la lisebelisoa tsa ho lemoha bakeng sa ho lemoha mofuta oa tumor, ho fana ka tharollo e akaretsang bakeng sa kalafo e lebisitsoeng ho tumor.
EGFR ea Motho Gene 29 Mutations Detection Kit (Fluorescence PCR)
Setsi sena se sebelisetsoa ho lemoha ka mokhoa o nepahetseng liphetoho tse tloaelehileng ho li-exons 18-21 tsa lefutso la EGFR ka lisampole ho tsoa ho bakuli ba mofetše oa matšoafo oa lisele tse seng nyane.
1. Sistimi e hlahisa taolo ea boleng ba litšupiso tsa kahare, e ka behang leihlo ka botlalo ts'ebetso ea liteko le ho netefatsa boleng ba teko.
2. Kutloelo-bohloko e phahameng: Ho fumanoa ha tharollo ea nucleic acid reaction ho ka khona ho lemoha ka mokhoa o tsitsitseng tekanyo ea phetoho ea 1% tlas'a semelo sa mofuta o hlaha oa 3ng / μL.
3. Boemo bo phahameng: Ha ho na karabelo e fapaneng le DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
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KRAS 8 Mutations Detection Kit (Fluorescence PCR)
Setsi sena se reretsoe ho lemoha boleng ba in vitro liphetoho tse 8 ho li-codon 12 le 13 tsa lefutso la K-ras ho DNA e nkiloeng likarolong tsa batho tse kentsoeng ke parafine.
1. Sistimi e hlahisa taolo ea boleng ba litšupiso tsa kahare, e ka behang leihlo ka botlalo ts'ebetso ea liteko le ho netefatsa boleng ba teko.
2. Kutloelo-bohloko e phahameng: Ho fumanoa ha tharollo ea nucleic acid reaction ho ka khona ho lemoha ka mokhoa o tsitsitseng tekanyo ea phetoho ea 1% tlas'a semelo sa mofuta o hlaha oa 3ng / μL.
3. Boemo bo phahameng: Ha ho na karabelo e fapaneng le DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
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Motho EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Setsi sena se sebelisetsoa ho lemoha ka mokhoa oa boleng mefuta e 12 ea phetoho ea EML4-ALK fusion ea lisampole tsa bakuli ba kankere ea matšoafo ea lisele tsa batho ba in vitro.
1. Sistimi e hlahisa taolo ea boleng ba litšupiso tsa kahare, e ka behang leihlo ka botlalo ts'ebetso ea liteko le ho netefatsa boleng ba teko.
2. Kutloelo-bohloko e phahameng: Setsi sena se ka lemoha liphetoho tsa fusion tse ka tlaase ho likopi tse 20.
3. Boemo bo phahameng: Ha ho na karabelo e fapaneng le DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
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Batho ba ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Setsi sena se sebelisetsoa ho lemoha boleng ba in vitro ea mefuta e 14 ea phetoho ea liphatsa tsa lefutso tsa ROS1 lisampoleng tsa mofetše oa matšoafo oa lisele tsa motho tse seng nyane.
1. Sistimi e hlahisa taolo ea boleng ba litšupiso tsa kahare, e ka behang leihlo ka botlalo ts'ebetso ea liteko le ho netefatsa boleng ba teko.
2. Kutloelo-bohloko e phahameng: Setsi sena se ka lemoha liphetoho tsa fusion tse ka tlaase ho likopi tse 20.
3. Boemo bo phahameng: Ha ho na karabelo e fapaneng le DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
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Human BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR)
Setsi sena sa liteko se sebelisetsoa ho bona ka mokhoa o nepahetseng phetoho ea mofuta oa BRAF V600E lisampoleng tsa lisele tse kentsoeng ka parafine tsa melanoma ea motho, mofetše oa mala, mofetše oa qoqotho le mofetše oa matšoafo ka har'a vitro.
1. Sistimi e hlahisa taolo ea boleng ba litšupiso tsa kahare, e ka behang leihlo ka botlalo ts'ebetso ea liteko le ho netefatsa boleng ba teko.
2. Kutloelo-bohloko e phahameng: Ho fumanoa ha tharollo ea nucleic acid reaction ho ka khona ho lemoha ka mokhoa o tsitsitseng tekanyo ea phetoho ea 1% tlas'a semelo sa mofuta o hlaha oa 3ng / μL.
3. Boemo bo phahameng: Ha ho na karabelo e fapaneng le DNA ea motho ea hlaha le mefuta e meng e fetotsoeng.
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| Nomoro ea lethathamo | Lebitso la Sehlahiswa | Tlhaloso |
| HWTS-TM012A/B | Motho EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR) | 16 liteko / kit, 32 liteko / kit |
| HWTS-TM014A/B | KRAS 8 Mutations Detection Kit(Fluorescence PCR) | 24 liteko / kit, 48 liteko / kit |
| HWTS-TM006A/B | Motho EML4-ALK Fusion Gene Mutation Detection Kit(Fluorescence PCR) | 20 liteko / kit, 50 liteko / kit |
| HWTS-TM009A/B | Batho ba ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 liteko / kit, 50 liteko / kit |
| HWTS-TM007A/B | Human BRAF Gene V600E Mutation Detection Kit(Fluorescence PCR) | 24 liteko / kit, 48 liteko / kit |
| HWTS-GE010A | Human BCR-ABL Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 liteko/kit |
Nako ea poso: Apr-17-2023